An intraoperative brain-shift monitor using shear-mode transcranial ultrasound: Preliminary results

A device that uses the shear mode of transcranial ultrasound transmission for intraoperative monitoring has been designed, constructed, and tested with 10 human subjects. Magnetic resonance (MR) images were obtained with the device spatially registered to the MR reference coordinates. Peaks in both...

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Bibliographic Details
Published in2008 IEEE Ultrasonics Symposium pp. 1363 - 1365
Main Authors White, P.J., Whalen, S., Tang, S.C., Clement, G.T., Jolesz, F.A., Golby, A.J.
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.11.2008
Subjects
brain shift
Humans
Magnetic analysis
Magnetic resonance
monitor
Monitoring
neurosurgery
Prototypes
Signal analysis
Signal processing
Signal to noise ratio
Testing
transcranial
Ultrasonic imaging
ultrasound
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Summary:A device that uses the shear mode of transcranial ultrasound transmission for intraoperative monitoring has been designed, constructed, and tested with 10 human subjects. Magnetic resonance (MR) images were obtained with the device spatially registered to the MR reference coordinates. Peaks in both the ultrasound and MR signals were identified and analyzed both for spatial localization and signal-to-noise ratio (SNR). The first results aimed towards validating the prototype device against MRI have demonstrated excellent correlation (n = 38, R 2 = 0.9962) between the structural localization abilities of the two modalities. In addition, the overall SNR of the ultrasound backscatter signals (n = 38, SNR = 25.4plusmn5.2 dB) was statistically equivalent to that of the MR data (n = 38, SNR = 22.5plusmn4.8 dB).
ISBN:1424424283
9781424424283
ISSN:1051-0117
DOI:10.1109/ULTSYM.2008.0330