Red-emitting substrates for rapid botulinum neurotoxin detection

We report a new red-emitting molecular beacon for botulinum neurotoxin A suitable inexpensive rapid assay formats. Reaction kinetics including parameters like K m and V max were evaluated in a fluorogenic assay using the BoNT/A light chain.

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Bibliographic Details
Published inCLEO: 2013 pp. 1 - 2
Main Authors Herron, James N., Engelhardt, Konrad H., O'Mel, Vlad
Format Conference Proceeding
LanguageEnglish
Published The Optical Society 01.06.2013
Subjects
Biomedical optical imaging
Fluorescence
Kinetic theory
Optical sensors
Proteins
Substrates
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Summary:We report a new red-emitting molecular beacon for botulinum neurotoxin A suitable inexpensive rapid assay formats. Reaction kinetics including parameters like K m and V max were evaluated in a fluorogenic assay using the BoNT/A light chain.
ISSN:2160-8989
2160-9004