Leporine model refinement for investigation of an ophthalmic dynamic light scattering instrument

Evaluation of lens opacity is indispensable in human clinical monitoring as well as research. The rapid evolution of ophthalmic instrumentation impels the development of models which are anatomically and physiologically realistic; and, at the same time, minimally intrusive to the nonhuman animal sub...

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Bibliographic Details
Published inNortheast Bioengineering Conference, 1998 pp. 45 - 48
Main Authors Dubin, S., Ansari, R.R., Victor, M., Koch, S., Steinberg, S., VanWinkel, T., Della Vecchia, M.
Format Conference Proceeding
LanguageEnglish
Published IEEE 1998
Subjects
Animals
Biomedical monitoring
Humans
Instruments
Lenses
Light scattering
Medical diagnostic imaging
NASA
Rabbits
Testing
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ISBN9780780345447
0780345444
DOI10.1109/NEBC.1998.664872

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Summary:Evaluation of lens opacity is indispensable in human clinical monitoring as well as research. The rapid evolution of ophthalmic instrumentation impels the development of models which are anatomically and physiologically realistic; and, at the same time, minimally intrusive to the nonhuman animal subjects. Use of an appropriate dosage regimen and other technical refinements for administration of naphthalene in the rabbit can reliably cause lens opacity and chorioretinal changes with much diminished danger or distress.
ISBN:9780780345447
0780345444
DOI:10.1109/NEBC.1998.664872