Optical trapping of microspheres as a model for biological cells

An analytical model has been developed to predict, in three dimensions, the forces exerted on dielectric microspheres in an optical trap. Results for a single-beam gradient force trap predict the existence of a stable trapping location and an effective trapping range. A minimum trapping power of app...

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Bibliographic Details
Published inImages of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society pp. 1203 - 1204 vol.4
Main Authors Wright, W.H., Sonek, G.J., Berns, M.W.
Format Conference Proceeding
LanguageEnglish
Published IEEE 1989
Subjects
Biological cells
Biological system modeling
Biomedical optical imaging
Charge carrier processes
Dielectrics
Laser beams
Optical beams
Optical scattering
Surface emitting lasers
Surface waves
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Summary:An analytical model has been developed to predict, in three dimensions, the forces exerted on dielectric microspheres in an optical trap. Results for a single-beam gradient force trap predict the existence of a stable trapping location and an effective trapping range. A minimum trapping power of approximately 5 mW, and an effective axial range of approximately 9 mu m, have been measured for polystyrene microspheres suspended in water and are in reasonable agreement with theoretical results. Applications of the model to the optical trapping of biological cells and chromosomes are described.< >
DOI:10.1109/IEMBS.1989.96160