A rare case of a multifocal extra-adrenal myelolipoma with markedly hypocellular bone marrow

Extra-adrenal myelolipomas are rare, generally solitary, non-functioning tumors consisting of adipose tissue and hematopoetic elements. These lesions are not known to be associated with underlying hematologic disorders or documented bone marrow abnormalities. We describe the extremely rare occurrenc...

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Bibliographic Details
Published inAnnals of clinical and laboratory science Vol. 36; no. 2; pp. 208 - 211
Main Authors Sawhney, Rishi, McRae, Bart, Lazarchick, John
Format Journal Article
LanguageEnglish
Published United States 2006
Subjects
Adult
Bone Marrow - pathology
Diagnosis, Differential
Hematopoiesis, Extramedullary - physiology
Humans
Kidney Neoplasms - diagnosis
Kidney Neoplasms - pathology
Male
Mediastinal Neoplasms - diagnosis
Mediastinal Neoplasms - pathology
Myelolipoma - diagnosis
Myelolipoma - therapy
Neoplasms, Multiple Primary - diagnosis
Neoplasms, Multiple Primary - therapy
Tomography, X-Ray Computed
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Summary:Extra-adrenal myelolipomas are rare, generally solitary, non-functioning tumors consisting of adipose tissue and hematopoetic elements. These lesions are not known to be associated with underlying hematologic disorders or documented bone marrow abnormalities. We describe the extremely rare occurrence of multifocal, extra-adrenal myelolipomas in a 35-yr-old male. A markedly hypocellular bone marrow is noted, despite normal peripheral blood counts. To our knowledge, this is the first case report of a markedly abnormal marrow examination in a patient with extra-adrenal myelolipoma, and implicates the extra-osseous masses as the driving force behind his normal hematopoesis.
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ISSN:0091-7370