Central Nervous System Extraosseous Ewing Sarcoma: Radiologic Manifestations of This Newly Defined Pathologic Entity

Although these entities are histologically similar, recent advances in molecular genetics have allowed the distinction of central nervous system extraosseous Ewing sarcoma (CNS-EES) from central primitive neuroectodermal tumors (c-PNET) including medulloblastoma and supratentorial PNET. We present 2...

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Published inAmerican Journal of Neuroradiology Vol. 27; no. 3; pp. 580 - 583
Main Authors Pekala, J.S, Gururangan, S, Provenzale, J.M, Mukundan, S., Jr
Format Journal Article
LanguageEnglish
Published Oak Brook, IL Am Soc Neuroradiology 01.03.2006
American Society of Neuroradiology
Subjects
Biological and medical sciences
Brain Neoplasms - diagnostic imaging
Child
Electrocardiography. Vectocardiography
Electrodiagnosis. Electric activity recording
Eye
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Nervous system
Pediatrics
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radionuclide investigations
Sarcoma, Ewing - diagnostic imaging
Tomography, X-Ray Computed
Ewing sarcoma
Nervous system diseases
Malignant tumor
Radiodiagnosis
Diseases of the osteoarticular system
Central nervous system
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Summary:Although these entities are histologically similar, recent advances in molecular genetics have allowed the distinction of central nervous system extraosseous Ewing sarcoma (CNS-EES) from central primitive neuroectodermal tumors (c-PNET) including medulloblastoma and supratentorial PNET. We present 2 cases of pathologically confirmed CNS-EES. Knowledge of CNS-EES as a distinct entity enables the neuroradiologist to suggest the proper diagnosis and the need for special immuno-histochemical and molecular studies to confirm the diagnosis. Because treatment and prognosis are vastly different, the proper diagnosis of CNS-EES versus c-PNET is critical.
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ISSN:0195-6108
1936-959X
1432-1920