Donor buffy-coat infusion and chemotherapy for leukemia in relapse after marrow transplantation

Department of Internal Medicine, Medical School, Zagreb, Croatia. A patient relapsing with blastic lymphoid transformation of chronic myeloid leukemia after bone marrow transplantation received donor buffy-coat infusion. Low-dose chemotherapy was added because of a rapid WBC increase. Complete hemat...

Full description

Saved in:
Bibliographic Details
Published inHaematologica (Roma) Vol. 80; no. 4; pp. 338 - 340
Main Authors Bogdanic, V, Aurer, I, Hitrec, V, Boban, D, Nemet, D, Zupancic-Salek, S, Labar, B
Format Journal Article
LanguageEnglish
Published Pavia Haematologica 01.07.1995
Subjects
Acute Disease
Adult
Antineoplastic agents
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Blast Crisis - drug therapy
Blast Crisis - therapy
Bone Marrow Transplantation
Combined Modality Therapy
Combined treatments (chemotherapy of immunotherapy associated with an other treatment)
Cytarabine - administration & dosage
Daunorubicin - administration & dosage
Fatal Outcome
Female
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy
Leukemia, Myeloid - therapy
Leukocyte Transfusion
Male
Medical sciences
Methylprednisolone - administration & dosage
Pharmacology. Drug treatments
Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy
Remission Induction
Salvage Therapy
Vincristine - administration & dosage
Chromosomal aberration
Antineoplastic agent
Relapse
Transfusion
Homograft
Blast transformation
Methylprednisolone
Glucocorticoid
Myeloproliferative syndrome
Alkaloid
Chronic myelocytic leukemia
Bone marrow
Graft
Human
Corticosteroid
Ph1-Chromosome
Steroid hormone
Low dose
Malignant hemopathy
Case study
Chemotherapy
Chronic
Adrenal hormone
Young adult
Abnormal chromosome
Combined treatment
Online AccessGet full text

Cover

More Information
Summary:Department of Internal Medicine, Medical School, Zagreb, Croatia. A patient relapsing with blastic lymphoid transformation of chronic myeloid leukemia after bone marrow transplantation received donor buffy-coat infusion. Low-dose chemotherapy was added because of a rapid WBC increase. Complete hematologic and cytogenetic remission was obtained. The patient remained in complete hematologic and cytogenetic remission for four months until he died in an accident. Two patients with acute leukemia failed to respond to a similar treatment.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Case Study-2
ObjectType-Feature-4
ObjectType-Report-1
ObjectType-Article-3
ISSN:0390-6078
1592-8721