Jod-Basedow Syndrome Following Oral Iodine and Radioiodinated-Antibody Administration

This is a case of thyrotoxicosis, presumably due to Jod-Basedow syndrome, after stable iodine ingestion for thyroid blockade in a patient with ovarian carcinoma having 131I-labeled monoclonal antibody imaging. With the increased use of radioiodinated antibodies, for therapy and imaging, this possibl...

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Bibliographic Details
Published inThe Journal of nuclear medicine (1978) Vol. 38; no. 11; pp. 1816 - 1817
Main Authors El-Shirbiny, Ayda M, Stavrou, Stavross S, Dnistrian, Ann, Sonenberg, Martin, Larson, Steven M, Divgi, Chaitanya R
Format Journal Article
LanguageEnglish
Published Reston, VA Soc Nuclear Med 01.11.1997
Society of Nuclear Medicine
Subjects
Aged
Biological and medical sciences
Endocrinopathies
Female
Humans
Iodine Radioisotopes
Medical sciences
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Ovarian Neoplasms - diagnostic imaging
Potassium Iodide - administration & dosage
Potassium Iodide - adverse effects
Radioimmunodetection - adverse effects
Syndrome
Thyroid. Thyroid axis (diseases)
Thyrotoxicosis - chemically induced
Thyrotoxicosis - diagnostic imaging
Endocrinopathy
Human
Immunopathology
Carcinoma
Radiolabelling
Hyperthyroidism
Thyroid diseases
Autoimmune disease
Malignant tumor
Monoclonal antibody
Female genital diseases
Ingestion
Case study
Ovarian diseases
Ovary
Association
Graves disease
Female
Iodine
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Summary:This is a case of thyrotoxicosis, presumably due to Jod-Basedow syndrome, after stable iodine ingestion for thyroid blockade in a patient with ovarian carcinoma having 131I-labeled monoclonal antibody imaging. With the increased use of radioiodinated antibodies, for therapy and imaging, this possible side effect of excess stable iodine administration should be noted, especially in patients with pre-existing goiter.
ISSN:0161-5505
1535-5667