Acute nonlymphocytic leukemia following bladder instillations with thiotepa

A case of therapy-related leukemia is described. Other cases of acute nonlymphocytic leukemia have been associated with the intramuscular administration of thiotepa (an alkylating agent), but this patient received only intravesical instillations of the drug. The interval between the start of chemoth...

Full description

Saved in:
Bibliographic Details
Published inCanadian Medical Association journal Vol. 129; no. 6; pp. 578 - 579
Main Authors Easton, D. J, Poon, M. A
Format Journal Article
LanguageEnglish
Published Canada Can Med Assoc 15.09.1983
Subjects
Acute Disease
Aged
Humans
Leukemia - chemically induced
Male
Papilloma - drug therapy
Thiotepa - administration & dosage
Thiotepa - adverse effects
Time Factors
Urinary Bladder
Urinary Bladder Neoplasms - drug therapy
Online AccessGet full text

Cover

More Information
Summary:A case of therapy-related leukemia is described. Other cases of acute nonlymphocytic leukemia have been associated with the intramuscular administration of thiotepa (an alkylating agent), but this patient received only intravesical instillations of the drug. The interval between the start of chemotherapy and the onset of leukemia was 56 months.
ISSN:0008-4409