Synthesis and reactivity of 2,3-dihydro-1H-2,3-benzodiazepine-1,4(5H)-dione
Based on an orthogonal protective group strategy dealing with N-protected hydrazine, we established for the first time a highly efficient synthetic pathway leading to 2,3-benzodiazepine-1,4-dione. Moreover, the versatile reactivities exhibited by this 2,3-benzodiazepine-1,4-dione were evaluated towa...
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Published in | Synthesis (Stuttgart) no. 24; pp. 3791 - 3796 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
STUTTGART
Thieme Medical Publishers
17.12.2007
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Subjects | |
Online Access | Get more information |
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Summary: | Based on an orthogonal protective group strategy dealing with N-protected hydrazine, we established for the first time a highly efficient synthetic pathway leading to 2,3-benzodiazepine-1,4-dione. Moreover, the versatile reactivities exhibited by this 2,3-benzodiazepine-1,4-dione were evaluated towards both benzylation and amination reactions. |
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ISSN: | 0039-7881 1437-210X |
DOI: | 10.1055/s-2007-990893 |