Severe "silent" mitral regurgitation. A potentially reversible cause of refractory heart failure

Hemodynamically critical ("severe") mitral regurgitation is usually associated with an audible (if not loud) systolic murmur and signs of left ventricular volume overload. However, "silent" severe mitral regurgitation is being increasingly recognized. We review the case histories...

Full description

Saved in:
Bibliographic Details
Published inChest Vol. 96; no. 2; p. 242
Main Authors Schreiber, T L, Fisher, J, Mangla, A, Miller, D
Format Journal Article
LanguageEnglish
Published United States 01.08.1989
Subjects
Adult
Aged
Cardiac Catheterization
Female
Heart Auscultation
Heart Failure - etiology
Heart Murmurs
Heart Valve Prosthesis
Humans
Male
Middle Aged
Mitral Valve
Mitral Valve Insufficiency - complications
Mitral Valve Insufficiency - diagnosis
Mitral Valve Insufficiency - surgery
Online AccessGet more information

Cover

More Information
Summary:Hemodynamically critical ("severe") mitral regurgitation is usually associated with an audible (if not loud) systolic murmur and signs of left ventricular volume overload. However, "silent" severe mitral regurgitation is being increasingly recognized. We review the case histories of nine patients with silent hemodynamically important mitral regurgitation (associated with acute myocardial infarction and chronic valvular, hypertrophic, and ischemic heart disease), six of whom survived mitral valve replacement, of whom five are alive and functioning well more than three years postoperatively. Performance of left ventriculography early in the hospital course of patients with severe unexplained congestive heart failure (with normal or near-normal left ventricular systolic function assessed noninvasively) identifies patients with severe silent mitral regurgitation who may have long-term benefit from mechanical therapy.
ISSN:0012-3692
DOI:10.1378/chest.96.2.242