Myeloproliferative disease in the pathogenesis and survival of Budd-Chiari syndrome

We studied the etiology, diagnosis and natural course of myeloproliferative disease (MPD) in 40 consecutive patients with Budd-Chiari syndrome (BCS). In 38% of the BCS patients with MPD another etiological factor was found. JAK2 mutation was present in 41% of the tested BCS patients. Survival was no...

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Published inHaematologica (Roma) Vol. 91; no. 12; pp. 1712 - 1713
Main Authors Smalberg, JH, Murad, SD, Braakman, E, Valk, PJ, Janssen, HL, Leebeek, FW
Format Journal Article
LanguageEnglish
Published Pavia Haematologica 01.12.2006
Subjects
Adult
Biological and medical sciences
Budd-Chiari Syndrome - etiology
Budd-Chiari Syndrome - mortality
Female
Gastroenterology. Liver. Pancreas. Abdomen
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Middle Aged
Myeloproliferative Disorders - complications
Myeloproliferative Disorders - mortality
Other diseases. Semiology
Survival Analysis
Vascular disease
Myeloproliferative syndrome
Portal circulation disease
Hematology
Pathogenesis
Budd Chiari syndrome
Cardiovascular disease
Digestive diseases
Hemopathy
Survival
Venous disease
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Summary:We studied the etiology, diagnosis and natural course of myeloproliferative disease (MPD) in 40 consecutive patients with Budd-Chiari syndrome (BCS). In 38% of the BCS patients with MPD another etiological factor was found. JAK2 mutation was present in 41% of the tested BCS patients. Survival was not significantly affected by the presence of MPD.
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ObjectType-Correspondence-1
ISSN:0390-6078
1592-8721