MRI Diagnosis of Mesorectal Lymph Node Metastasis in Patients with Rectal Carcinoma. What is the Optimal Criterion?

Background: Preoperative diagnosis of lymph node metastasis is often difficult. A number of different criteria have been advocated in the literature, however, an optimal criterion has not yet been determined in patients with rectal carcinoma. Patients and Methods: Fifty-one patients, undergoing radi...

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Published inAnticancer research Vol. 24; no. 6; pp. 4097 - 4101
Main Authors MATSUOKA, Hiroyoshi, NAKAMURA, Akihisa, SUGIYAMA, Masanori, HACHIYA, Junichi, ATOMI, Yutaka, MASAKI, Tadahiko
Format Journal Article
LanguageEnglish
Published Attiki International Institute of Anticancer Research 01.11.2004
Subjects
Biological and medical sciences
Female
Humans
Lymph Nodes - pathology
Lymphatic Metastasis
Magnetic Resonance Imaging
Male
Medical sciences
Middle Aged
Preoperative Care
Rectal Neoplasms - diagnosis
Rectal Neoplasms - pathology
Rectal Neoplasms - surgery
ROC Curve
Tumors
Human
Rectal disease
MRI
rectal cancer
Malignant lymphadenopathy
Malignant tumor
Nuclear magnetic resonance imaging
Cancerology
Criterion
Digestive diseases
Medical imagery
Intestinal disease
Diagnosis
lymph node metastasis
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Summary:Background: Preoperative diagnosis of lymph node metastasis is often difficult. A number of different criteria have been advocated in the literature, however, an optimal criterion has not yet been determined in patients with rectal carcinoma. Patients and Methods: Fifty-one patients, undergoing radical surgery with total mesorectal excision, were examined with reference to regional lymph node status. MRI and pathological findings were compared, and an optimal preoperative criterion was clarified by receiver operating characteristic (ROC) analysis. Results: Among size, shape and internal structure criteria, size was a significant factor for diagnosing metastatic lymph node on MRI. ROC analysis showed that a criterion of 6-mm or larger in the longitudinal axis was the most reliable in differentiating metastatic and non-metastatic lymph nodes, with overall accuracy of 78%. Conclusion: A 6-mm longitudinal diameter criterion is thought to be most optimal in the evaluation of mesorectal lymph node status in patients with rectal carcinoma.
Bibliography:ObjectType-Article-2
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ISSN:0250-7005
1791-7530