Kikuchi's disease accompanied by lupus-like butterfly rash

Kikuchi's disease (KD) is a benign and self-limiting lymphadenitis, particularly affecting young women. KD is often associated with fever, arthralgia, and leukopenia, features also found in systemic lupus erythematosus (SLE). Lymphadenitis associated with SLE is indistinguishable from that in K...

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Bibliographic Details
Published inJournal of rheumatology Vol. 30; no. 4; p. 857
Main Authors Okuzawa, Chie, Kuroiwa, Takashi, Kaneko, Yoriaki, Ueki, Kazue, Tsukada, Yoshito, Nojima, Yoshihisa
Format Journal Article
LanguageEnglish
Published Canada 01.04.2003
Subjects
Adolescent
Diagnosis, Differential
Exanthema - diagnosis
Female
Histiocytic Necrotizing Lymphadenitis - pathology
Humans
Lupus Erythematosus, Systemic - diagnosis
Lymph Nodes - pathology
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Summary:Kikuchi's disease (KD) is a benign and self-limiting lymphadenitis, particularly affecting young women. KD is often associated with fever, arthralgia, and leukopenia, features also found in systemic lupus erythematosus (SLE). Lymphadenitis associated with SLE is indistinguishable from that in KD, and the association of KD and SLE has been previously reported. We describe a case of KD who developed a typical butterfly rash, reminiscent of SLE. However, histological and laboratory findings excluded the diagnosis of SLE. This case emphasizes that careful differential diagnosis between KD and SLE is required.
ISSN:0315-162X