Innovative Approach in the Diagnosis of Gliomatosis Cerebri Using Carbon-11-L-Methionine Positron Emission Tomography

A case of gliomatosis cerebri was studied with positron emission tomography (PET). Carbon-11-L-methionine (11C-Met) accumulated in the diffusely infiltrative tumorous area more widely and accurately than the lesion detected by conventional x-ray computerized tomography (CT) or magnetic resonance (MR...

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Bibliographic Details
Published inThe Journal of nuclear medicine (1978) Vol. 32; no. 4; pp. 726 - 728
Main Authors Mineura, Katsuyoshi, Sasajima, Toshio, Kowada, Masayoshi, Uesaka, Yoshiyuki, Shishido, Fumio
Format Journal Article
LanguageEnglish
Published United States Soc Nuclear Med 01.04.1991
Subjects
ACCURACY
Adult
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
BRAIN
Brain Neoplasms - diagnostic imaging
CARBON 11
CARBON ISOTOPES
Carbon Radioisotopes
CARBOXYLIC ACIDS
CENTRAL NERVOUS SYSTEM
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
Female
Glioma - diagnostic imaging
GLIOMAS
Humans
ISOTOPES
LIGHT NUCLEI
LIPOTROPIC FACTORS
METHIONINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NERVOUS SYSTEM
NMR IMAGING
NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
RADIOISOTOPES
RADIOLOGY AND NUCLEAR MEDICINE
TOMOGRAPHY 550601 > Medicine > Unsealed Radionuclides in Diagnostics
Tomography, Emission-Computed
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Summary:A case of gliomatosis cerebri was studied with positron emission tomography (PET). Carbon-11-L-methionine (11C-Met) accumulated in the diffusely infiltrative tumorous area more widely and accurately than the lesion detected by conventional x-ray computerized tomography (CT) or magnetic resonance (MR) imaging. Autopsy findings three months after the time of the PET study showed good anatomical correspondence between the extent of densely aggregated tumor cells and the region with high uptake of 11C-Met. PET may offer an innovative approach in the delineation of gliomatosis cerebri, which has not been clearly recognized by CT or MR.
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ISSN:0161-5505
1535-5667