On-Chip Pre-Treatment of Biological Samples for the Isolation of Adipose Stem Cells (ASCs)

This study presents the development of an original 2-steps Lab-on-chip that aims at isolating Adipose Stem Cells (ASCs), cells of considerable interest for regenerative medicine, from complex biological samples. Based on hydrodynamic filtration, the device pre-isolates ASCs by removing cells with a...

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Published in2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII) pp. 740 - 743
Main Authors Valette, Marion, Bouguelmouna, Mathias, Mariotte, Melanie, Courson, Remi, Blatche, Marie-Charline, Girousse, Amandine, Sengenes, Coralie, Reybier, Karine, Gue, Anne-Marie
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.06.2019
Subjects
Adipose Stem Cells
Cells (biology)
Dry Films
Filtration
Fluorescence
Glass
Hydrodynamic Filtration
Hydrodynamics
Microfluidics
Stem cells
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Summary:This study presents the development of an original 2-steps Lab-on-chip that aims at isolating Adipose Stem Cells (ASCs), cells of considerable interest for regenerative medicine, from complex biological samples. Based on hydrodynamic filtration, the device pre-isolates ASCs by removing cells with a diameter below 10µm such as red blood cells or lymphocytes.
ISSN:2167-0021
DOI:10.1109/TRANSDUCERS.2019.8808694