Impact of respiratory motion correction on the detection of small lesions in whole-body PET imaging: A simulation study

Respiratory motion in Positron Emission Tomography leads to reduced image quality, influencing this way the quantitative accuracy of PET measurements, as shown in numerous studies. However, only few results have been published on its impact on lesion detection. This study intends to evaluate the imp...

Full description

Saved in:
Bibliographic Details
Published inIEEE Nuclear Science Symposuim & Medical Imaging Conference pp. 3531 - 3533
Main Authors Marache-Francisco, S, Lamare, F, Fayad, H, Visvikis, D, Prost, R, Rouet, J.-M, Lartizien, C
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.10.2010
Subjects
Image reconstruction
Lesions
Liver
Lungs
Positron emission tomography
Solid modeling
Online AccessGet full text

Cover

More Information
Summary:Respiratory motion in Positron Emission Tomography leads to reduced image quality, influencing this way the quantitative accuracy of PET measurements, as shown in numerous studies. However, only few results have been published on its impact on lesion detection. This study intends to evaluate the impact of motion correction on the detection of small lesions (between 8 and 12 mm diameter) using a Computed-Aided Detection (CAD) system on FDG whole-body simulated PET images. We evaluate two types of motion correction techniques, both using motion fields derived from the reconstruction of gated PET images. The first technique consists in averaging the coregistered gated reconstructed PET images, while the second method integrates the motion fields during the iterative reconstruction process.
ISBN:9781424491063
1424491061
ISSN:1082-3654
2577-0829
DOI:10.1109/NSSMIC.2010.5874465