Neurological and psychiatric aspects of corpus callosum genesis

• Published in: Psychiatria Danubina Vol. 22; no. 2; pp. 282 - 285
• Main Authors: Sepić-Grahovac, Dubravka, Ruzić Barsić, Antonija, Ruzić, Klementina, Grahovac, Tanja, Dadić-Hero, Elizabeta
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Croatia Medicinska naklada 01.06.2010
• Subjects: Acrocallosal Syndrome - diagnosis; Acrocallosal Syndrome - drug therapy; Acrocallosal Syndrome - physiopathology; Acrocallosal Syndrome - psychology; Adult; Amnesia - diagnosis; Amnesia - drug therapy; Amnesia - physiopathology; Amnesia - psychology; Anticonvulsants - therapeutic use; Apraxias - diagnosis; Apraxias - drug therapy; Apraxias - physiopathology; Apraxias - psychology; corpus callosum; epilepsy; Epilepsy, Generalized - diagnosis; Epilepsy, Generalized - drug therapy; Epilepsy, Generalized - physiopathology; Epilepsy, Generalized - psychology; Functional Laterality - physiology; Humans; Leg Length Inequality - diagnosis; Leg Length Inequality - physiopathology; Leg Length Inequality - psychology; Magnetic Resonance Imaging; Male; Neurologic Examination; Neuropsychological Tests; Paranoid Disorders - diagnosis; Paranoid Disorders - drug therapy; Paranoid Disorders - physiopathology; Paranoid Disorders - psychology; Pyramidal Tracts - physiopathology; Syndrome; Triazines - therapeutic use
• ISSN: 0353-5053; 1849-0867

This article reports the case of a patient with partial agenesis of the corpus callosum manifested with corpus callosum syndrome together with signs of brain hemispheres dysfunction: mental impairment, epilepsy and pyramidal signs. The patient's malformation is combined with left-handedness while signs of callosal disconnection are not present. Mild cognitive impairment and late epilepsy onset require a multidisciplinary approach since the patient also displays elements of central nervous system malformations.