BARBITURATES AS SPINAL ANESTHETICS

Four barbiturates, namely, pentobarbital, secobarbital, barbital, and thiopental (0.05 ml. of 5 per cent/kgm.), have been used as spinal anesthetics in dogs. These compounds produced complete spinal block persisting approximately the same length of time as resulted from the same volume of 2 per cent...

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Published inThe Journal of pharmacology and experimental therapeutics Vol. 118; no. 3; pp. 318 - 321
Main Authors PURDY, F A, WESTFALL, B A
Format Journal Article
LanguageEnglish
Published United States American Society for Pharmacology and Experimental Therapeutics 01.11.1956
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Summary:Four barbiturates, namely, pentobarbital, secobarbital, barbital, and thiopental (0.05 ml. of 5 per cent/kgm.), have been used as spinal anesthetics in dogs. These compounds produced complete spinal block persisting approximately the same length of time as resulted from the same volume of 2 per cent procaine solution. No undesirable side effects, either during or after the anesthesia, were observed. It is suggested that these compounds should not be used intrathecally in man for complications have been reported following spinal anesthesia with barbiturates in man.
Bibliography:ObjectType-Article-1
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ISSN:0022-3565
1521-0103