Surface and cytoplasmic antigens in retinoblastoma

Surface and cytoplasmic antigens in retinoblastoma were examined by antisera prepared against two tissue-cultured retinoblastoma cell lines. In addition, several other antisera, including anti-rhodopsin, anti-rod outer segment, anti-large-molecular-weight protein, anti-S, and anti-P antigen, were al...

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Bibliographic Details
Published inInvestigative ophthalmology & visual science Vol. 19; no. 10; p. 1242
Main Authors Felberg, NT, Donoso, LA
Format Journal Article
LanguageEnglish
Published United States ARVO 01.10.1980
Subjects
Antigens, Neoplasm - analysis
Antigens, Surface - analysis
Cells, Cultured
Cross Reactions
Cytoplasm - immunology
Cytotoxicity Tests, Immunologic
Eye Neoplasms - immunology
Humans
Retinoblastoma - immunology
Rod Cell Outer Segment - immunology
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Summary:Surface and cytoplasmic antigens in retinoblastoma were examined by antisera prepared against two tissue-cultured retinoblastoma cell lines. In addition, several other antisera, including anti-rhodopsin, anti-rod outer segment, anti-large-molecular-weight protein, anti-S, and anti-P antigen, were also utilized in a complement-dependent cytotoxicity assay in order to explore the tumor cell surface. Antisera to tissue-cultured retinoblastoma cell lines were cross-reactive to both cell lines as was rod outer segment antiserum.
ISSN:0146-0404
1552-5783