Manganese-52m, A New Short-Lived, Generator-Produced Radionuclide: A Potential Tracer for Positron Tomography

• Published in: The Journal of nuclear medicine (1978) Vol. 21; no. 6; pp. 565 - 569
• Main Authors: Atcher, Robert W, Friedman, Arnold M, Huizenga, John R, Rayudu, G. V. S, Silverstein, Edward A, Turner, David A
• Format: Journal Article
• Language: English
• Published: United States Soc Nuclear Med 01.06.1980
• Subjects: Animals; Female; Manganese - metabolism; Mice; Radioisotopes; Radionuclide Generators; Tissue Distribution; Tomography, Emission-Computed

A new generator system has been developed using the Fe-52 leads to Mn-52m parent-daughter pair. Fe-52, half-life 8.3 hr, is isolated on an anion-exchange column, and Mn-52m is eluted in hydrochloric acid. Breakthrough is less than 0.01% and the yield is 75%. The 21.1-min half life of Mn-52m is ideal...