Glutamatergic System in Bone Physiology

Bone is a highly innervated tissue consisting of nerve fibers, which contain many neurotransmitters including glutamate. Recently, a number of studies have identified functional glutamate receptors in osteoblasts and osteoclasts, implying that the glutamatergic system has an apparent regulatory role...

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Bibliographic Details
Published inIn vivo (Athens) Vol. 18; no. 5; pp. 621 - 628
Main Authors Kalariti, Niki, Koutsilieris, Michael
Format Journal Article
LanguageEnglish
Published Greece International Institute of Anticancer Research 01.09.2004
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Summary:Bone is a highly innervated tissue consisting of nerve fibers, which contain many neurotransmitters including glutamate. Recently, a number of studies have identified functional glutamate receptors in osteoblasts and osteoclasts, implying that the glutamatergic system has an apparent regulatory role in bone physiology. This review outlines the evidence which suggest that the glutamatergic system regulates bone physiology.
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ISSN:0258-851X
1791-7549