Effect of Narcotic Premedication on Scintigraphic Evaluation of Gallbladder Perforation

A case of gallbladder perforation is presented in which a small bile leak was demonstrated by cholescintigraphy while the patient was receiving meperidine, but not after meperidine was discontinued. The scintigrams obtained during meperidine therapy also showed a pattern of bile-duct obstruction. It...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of nuclear medicine (1978) Vol. 26; no. 1; pp. 51 - 53
Main Authors Sefczek, Donna M, Sharma, Purna, Isaacs, Gilbert H, Brodmerkel, George J., Jr, Adatepe, Mustafa H, Powell, Oscar M, Nichols, Kenneth
Format Journal Article
LanguageEnglish
Published United States Soc Nuclear Med 01.01.1985
Subjects
Adult
Common Bile Duct - diagnostic imaging
Common Bile Duct - drug effects
Diagnosis, Differential
Gallbladder - diagnostic imaging
Gallbladder - injuries
Humans
Imino Acids
Male
Meperidine - pharmacology
Meperidine - therapeutic use
Premedication
Punctures
Radionuclide Imaging
Technetium
Technetium Tc 99m Disofenin
Online AccessGet full text

Cover

More Information
Summary:A case of gallbladder perforation is presented in which a small bile leak was demonstrated by cholescintigraphy while the patient was receiving meperidine, but not after meperidine was discontinued. The scintigrams obtained during meperidine therapy also showed a pattern of bile-duct obstruction. It is suggested that increased biliary pressure secondary to meperidine administration permitted visualization of the leak. Use of narcotic drugs may be a useful pharmacologic intervention in cases of peritonitis due to small or obscure bile leaks.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0161-5505
1535-5667