Acetabular Osteosarcoma Treated by Irradiation-vascularized Hybrid Bone Graft

• Published in: Anticancer research Vol. 24; no. 3B; pp. 1889 - 1892
• Main Authors: KUBO, Tadahiko, SUGITA, Takashi, SHIMOSE, Shoji, TANAKA, Haruyuki, NOBUTO, Hiroo, TANAKA, Kumi, OCHI, Mitsuo
• Format: Journal Article
• Language: English
• Published: Attiki International Institute of Anticancer Research 01.05.2004
• Subjects: Acetabulum - blood supply; Acetabulum - pathology; Acetabulum - surgery; Adolescent; Biological and medical sciences; Bone Neoplasms - pathology; Bone Neoplasms - surgery; Bone Transplantation - methods; Diseases of the osteoarticular system; Female; Fibula - blood supply; Fibula - surgery; Humans; Medical sciences; Osteosarcoma - pathology; Osteosarcoma - surgery; Reconstructive Surgical Procedures - methods; Transplantation, Autologous - methods; Tumors of striated muscle and skeleton; Sarcoma; Acetahular osteosarcoma. pelvic reconstruction; Diseases of the osteoarticular system; Hybrid; Acetabulum; Malignant tumor; irradiated osteoarticular graft; Osteoarticular system; Treatment; Osteosarcoma; Irradiation; Graft; Bone; vascularized fibula graft
• ISSN: 0250-7005; 1791-7530

Background: Periacetabular reconstruction after malignant bone tumor resection to preserve limb function is extremely challenging. The optimal reconstruction method has not yet received consensus and the functional outcomes still remain unsatisfactory. Case Report: A thirteen-year-old girl who was suffering from acetabular osteosarcoma was treated with wide excision of the tumor, followed by periacetabular reconstruction with an autogenous extracorporeal irradiated osteoarticular graft combined with a vascularized fibula graft. Incorporation of the irradiated pelvic bone was achieved despite infection and limb function turned out to be acceptable. Conclusion: This is the first report on an irradiation-vascularized hybrid autograft to reconstruct massive bone loss in primary limb-sparing surgery.