Image Registration of SPECT and CT Images Using an External Fiduciary Band and Three-Dimensional Surface Fitting in Metastatic Thyroid Cancer

Image registration of 131I SPECT with CT scans was performed in a patient with metastatic thyroid carcinoma using an external fiduciary band and a three-dimensional surface-fitting algorithim. Areas of metastatic disease taking up 131I were accurately localized to the liver, lungs and vertebral bodi...

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Bibliographic Details
Published inThe Journal of nuclear medicine (1978) Vol. 36; no. 1; pp. 100 - 103
Main Authors Scott, Andrew M, Macapinlac, Homer, Zhang, Jiaju, Daghighian, Farhad, Montemayor, Natalie, Kalaigian, Hovanes, Sgouros, George, Graham, Martin C, Kolbert, Katherine, Yeh, Samuel D.J, Lai, Eseng, Goldsmith, Stanley J, Larson, Steven M
Format Journal Article
LanguageEnglish
Published Reston, VA Soc Nuclear Med 01.01.1995
Society of Nuclear Medicine
Subjects
Algorithms
Biological and medical sciences
Carcinoma, Papillary, Follicular - diagnostic imaging
Carcinoma, Papillary, Follicular - pathology
Endocrine glands. Genital system. Mammary gland
Female
Humans
Image Interpretation, Computer-Assisted - methods
Investigative techniques, diagnostic techniques (general aspects)
Liver Neoplasms - secondary
Lung Neoplasms - secondary
Medical sciences
Middle Aged
Radionuclide investigations
Spinal Neoplasms - secondary
Thyroid Neoplasms - diagnostic imaging
Thyroid Neoplasms - pathology
Tomography, Emission-Computed, Single-Photon
Tomography, X-Ray Computed
Endocrinopathy
Radionuclide study
Human
3D imaging
Fitting
Thyroid diseases
Thyroid gland
Malignant tumor
Photon
Case study
Image analysis
Adult
Female
Edge detection
Computer aid
Iodine
Emission tomography
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Summary:Image registration of 131I SPECT with CT scans was performed in a patient with metastatic thyroid carcinoma using an external fiduciary band and a three-dimensional surface-fitting algorithim. Areas of metastatic disease taking up 131I were accurately localized to the liver, lungs and vertebral bodies; providing information that could not be obtained by planar or SPECT images alone. Based on these findings, further invasive diagnostic procedures were not performed, therefore considerably altering management in this patient. This approach to image registration has immediate clinical utility in the registration and interpretation of SPECT studies with corresponding CT or MRI scans.
Bibliography:ObjectType-Case Study-3
ObjectType-Article-1
SourceType-Scholarly Journals-1
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ObjectType-Report-2
ISSN:0161-5505
1535-5667