Presence of Adrenergic Receptors in the Uterus of Two Species of Lizards, Liolaemus gravenhorti and Liolaemus tenuis tenuis

• Published in: Biology of reproduction Vol. 5; no. 2; pp. 123 - 126
• Main Authors: Zurich, L, Paz de la Vega-Lemus, Y, Lemus, D
• Format: Journal Article
• Language: English
• Published: United States Society for the Study of Reproduction 01.10.1971
• Subjects: Animals; Epinephrine - antagonists & inhibitors; Female; Isoproterenol - antagonists & inhibitors; Isoproterenol - pharmacology; Lizards - physiology; Norepinephrine - antagonists & inhibitors; Phenoxybenzamine - pharmacology; Pregnancy; Receptors, Adrenergic; Receptors, Drug; Species Specificity; Stimulation, Chemical; Uterus - drug effects; Uterus - physiology
• ISSN: 0006-3363; 1529-7268

The effect of adrenalin, noradrenalin, or isoprenaline, alone or in the presence of an alpha (dibenzyline) or beta (dichlorisoproterenol) adrenergic blocking drugs, on isolated uterus from a viviparous lizard ( Liolaemus gravenhorti ) and an ovoviviparous one ( Liolaemus tenuis ), showed that both alpha and beta adrenergic receptors are present in the uterus of both species. Adrenalin and noradrenalin induced contraction, sometimes followed by relaxation, and this effect was blocked by dibenzyline. Isoprenaline always induced relaxation which was blocked by dichlorisoproterenol. These effects, with small differences, were observed in the uterus of both species, whether pregnant or not, although the sensitivity to the stimulation of both receptors appeared highest in the pregnant uterus of L. gravenhorti .