Alterations in p53 and p16INK4 expression and telomere length during spontaneous immortalization of Li-Fraumeni syndrome fibroblasts

• Published in: Molecular and Cellular Biology Vol. 15; no. 9; pp. 4745 - 4753
• Main Authors: Rogan, E M, Bryan, T M, Hukku, B, Maclean, K, Chang, A C, Moy, E L, Englezou, A, Warneford, S G, Dalla-Pozza, L, Reddel, R R
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.09.1995
• Subjects: Animals; Base Sequence; Carcinogenicity Tests; Carrier Proteins - genetics; Cell Transformation, Neoplastic - genetics; Cells, Cultured; Cellular Senescence - genetics; Chromosome Aberrations; Cyclin-Dependent Kinase Inhibitor p16; DNA Nucleotidylexotransferase - analysis; Fibroblasts; Heterozygote; Karyotyping; Li-Fraumeni Syndrome - enzymology; Li-Fraumeni Syndrome - genetics; Mice; Mice, Nude; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Ploidies; Retinoblastoma Protein - metabolism; Telomere - genetics; Telomere - metabolism; Tumor Suppressor Protein p53 - genetics
• ISSN: 0270-7306; 1098-5549

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