COVID-19 Associated Bacteremia with Chryseobacterium indologenes Co-Harboring [bla.sub.IND-2], [bla.sub.CIA] and [bla.sub.CcrA]

We report a COVID-19 case with carbapenem resistant Chryseobacterium indologenes bacteremia. Whole genome sequencing identified the presence of [bla.sub.IND-2], [bla.sub.CIA] and [bla.sub.CcrA]. To our knowledge, this is the first report of Chryseobacterium indologenes complicating COVID-19 and the...

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Bibliographic Details
Published inInfection and drug resistance Vol. 15; p. 167
Main Authors Yeh, Ting-Kuang, Li, Zong-Hao, Huang, Yao-Ting, Liu, Po-Yu
Format Journal Article
LanguageEnglish
Published Dove Medical Press Limited 31.01.2022
Subjects
Bacteremia
DNA sequencing
Drug resistance in microorganisms
Epidemics
Genomics
Health aspects
Imipenem
Infection
Nucleotide sequencing
Sulbactam
Tazobactam
World health
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Summary:We report a COVID-19 case with carbapenem resistant Chryseobacterium indologenes bacteremia. Whole genome sequencing identified the presence of [bla.sub.IND-2], [bla.sub.CIA] and [bla.sub.CcrA]. To our knowledge, this is the first report of Chryseobacterium indologenes complicating COVID-19 and the detection of [bla.sub.CcrA] in C. indologenes. The presence of [bla.sub.CcrA] in Chryseobacterium was overlooked previously may related to substantial sequence divergence with the original allele in Bacteroides fragilis. Antimicrobial resistance (AMR) is a challenge to global health in the age of COVID-19 pandemic. Further study and surveillance of underlying mechanisms is needed. Keywords: COVID-19, SARS-CoV-2, Chryseobacterium indologenes, resistance
ISSN:1178-6973
1178-6973
DOI:10.2147/IDR.S347066