Prescribing deprescription: a review for a virtuous circle/ Prescrever a desprescricao: uma revisao para um circulo virtuoso

• Published in: Revista de medicina (São Paulo, Brazil) Vol. 99; no. 4; p. 384
• Main Authors: Paganini Simoes, Vanessa, Vogt Rossi, Stephani, Andreatta, Thayna, Silva Faria, Jamille Sara, Bitencourt Moreira, Roberta, Hosken Pombo, Bruno
• Format: Journal Article
• Language: Portuguese
• Published: Universidade de Sao Paulo. Departamento Cientifico da Faculdade de Medicina 01.07.2020
• ISSN: 0034-8554
• DOI: 10.11606/issn.1679-9836.v99i4p384-388

Benzodiazepines (BZDs) are generally taken for treating anxiety, insomnia, alcohol abstinence, delirium, and convulsive crises due to their anxiolytic, hypnotic, anticonvulsive, and muscle relaxant activity. These medications must not be taken for more than two to four weeks, but it is common to see patients who take them for even up to 10 years. A review was performed based on NCBI/PubMed (National Center for Biotechnology Information) and SciELO (Scientific Electronic Library Online) databases to become familiar with proposed approaches on deprescriptions of BZDs. The results from the review show how heterogeneous the interventions are regarding the deprescription of BZDs and the need to improve the description to enable adequate replication in clinical practice and research studies. Keywords: Pescriptions drugs; Deprescriptions; Benzodiazepines. Os benzodiazepinicos (BZDs) geralmente sao utilizados no tratamento de ansiedade, insonia, abstinencia alcoolica, delirium e crises convulsivas devido sua atividade ansiolitica, hipnotica, anticonvulsivante e relaxante muscular. Esses medicamentos nao devem exceder duas a quatro semanas, mas e comum encontrar pacientes que usam por ate 10 anos. Com o objetivo de conhecer as abordagens propostas para desprescricao dos BZDs foi realizada uma revisao embasada nas bases de dados NCBI/PubMed (National Center for Biotechnology Information) e SciELO (Scientific Eletronic Lirary Online). Os resultados da revisao mostram o quao heterogenea sao as intervencoes a respeito da desprescricao de BZDs e a necessidade de melhor descricao para permitir uma adequada replicacao na pratica clinica e em pesquisas. Descritores: Medicamentos sob prescricao; Desprescricoes, Benzodiazepinas.