Effects of gonadotropins in female infertility associated with depression

Introduction: The relationship between LH and FSH changes and mental health is not clear yet, but may be independent of a strict diagnosis of infertility. Ongoing research has suggested that testosterone levels may play a role in brain development, which could provide a possible explanation for this...

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Published inBulletin of Integrative Psychiatry Vol. 26; no. 4; p. 77
Main Authors Barbu, Roxana Mihaela, Gavrilescu, Cristina-Maria, Stana, Bogdan, Popescu, Raducu Ionut, Catalin, Pohaci- Antonesei, Bild, Walther
Format Journal Article
LanguageEnglish
Published Institute of Psychiatry Socola, Iasi 01.12.2020
Subjects
Analysis
Depression, Mental
Follicle-stimulating hormone
Glycoproteins
Health care industry
Infertility
Luteinizing hormone
Medical research
Medicine, Experimental
Mental health
Psychological aspects
Testosterone
Romania
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Summary:Introduction: The relationship between LH and FSH changes and mental health is not clear yet, but may be independent of a strict diagnosis of infertility. Ongoing research has suggested that testosterone levels may play a role in brain development, which could provide a possible explanation for this association. Healthcare providers caring for women with infertility need to be aware that their patients may face many challenges when faced with infertility, such as depression. An in-depth assessment of the psychiatric needs of patients with infertility is crucial to provide specialized care to this category of patients. The aim of the study was to observe the possible implications of FSH and LH hormones in infertility and associated depression through studying the hormone levels in two Swiss mice groups and to compare these findings to the current literature. Materials and Methods: We used 20 Swiss nulliparous female mice and 15 Swiss multiparous female mice and we measured the luteinizing hormone and follicle-stimulating hormone in each group. Results: We observed a significant increase in mean LH and FSH in the multiparous group compared to the nulliparous group. In conclusion, significant differences in LH and FSH in the multiparous group compared to the nulliparous group and the presence of variations between the two groups of the studied mice suggest that a decrease in LH and FSH in nulliparous females could cause infertility that could also be associated with depression. KEYWORDS: Follicle-stimulating hormone, luteinizing hormone, infertility, depression.
ISSN:1453-7257