Incidental Detection of Sarcomatoid Lung Cancer by [ F] Choline Positron Emission Tomography/Computed Tomography/Sarkomatoid Akciger Kanserinin [[.sup.18F]] Kolin Pozitron Emisyon Tomografisi/Bilgisayarli Tomografi ile Rastlantisal Tespiti

A 79-year-old man treated for prostate cancer (PCa) in 2018 with concurrent hormone therapy and radical radiotherapy (RT) was given metastasis-directed RT because of skeletal progression of PCa in 2021. On [[.sup.18F]]-choline positron emission tomography/computed tomography (CT) for biochemical rec...

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Bibliographic Details
Published inMolecular imaging and radionuclide therapy Vol. 32; no. 3; p. 250
Main Authors Marco, Rensi, Capobianco, Decio, Fernando, Di Gregorio, Evangelista, Laura
Format Journal Article
LanguageEnglish
Published Galenos Yayinevi Tic. Ltd 01.10.2023
Subjects
Case studies
Choline
CT imaging
Diagnosis
Lung cancer
Lung cancer, Non-small cell
Metastasis
PET imaging
Prostate cancer
Italy
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Summary:A 79-year-old man treated for prostate cancer (PCa) in 2018 with concurrent hormone therapy and radical radiotherapy (RT) was given metastasis-directed RT because of skeletal progression of PCa in 2021. On [[.sup.18F]]-choline positron emission tomography/computed tomography (CT) for biochemical recurrence (prostate-specific antigen level: 4.96 ng/mL), he showed significant uptake in multiple skeletal lesions and focal uptake in a left lung nodule. CT-guided biopsy revealed a sarcomatoid lung carcinoma. This case confirms that histopathological evaluation is mandatory in the event of significant radiolabeled choline uptake in a single lung nodule. Keywords: Fluorocholine, cancer, interpretation 2018 yilinda prostat kanseri (PCa) nedeniyle eszamanli hormon tedavisi ve radikal radyoterapi (RT) ile tedavi edilen 79 yasindaki erkek hastaya, 2021 yilinda PCa'nin kemik tutulumu nedeniyle metastaz odakli RT uygulandi. Biyokimyasal nuks (prostat spesifik antijen duzeyi: 4,96 ng/mL) acisindan [[.sup.18F]]-kolin pozitron emisyon tomografisi/bilgisayarli tomografide (BT), coklu kemik lezyonlarinda belirgin tutulum ve sol akciger nodulunde fokal bir tutulum gosterildi. BT esliginde yapilan biyopside sarkomatoid akciger karsinomu saptandi. Bu olgu, tek bir akciger nodulunde anlamli radyoaktif isaretli kolin tutulumunun olmasi durumunda histopatolojik degerlendirmenin zorunlu oldugunu dogrulamaktadir. Anahtar kelimeler: Florokolin, kanser, yorum
ISSN:2146-1414
DOI:10.4274/mirt.galenos.2023.81594