ACUTE EFFECTS OF TRANSCRANIAL DIRECT CURRENT STIMULATION combinada com exercicio aerobico no tratamento da compulsao alimentar: um ensaio randomizado controlado

Purpose: To investigate whether one session of transcranial direct current (tDCS) stimulation alone or combined with aerobic exercise (AE) could reduce food consumption and the perception of hunger and satiety in patients with binge eating disorder. Materials and Methods: Adult individuals with BED...

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Published inRevista brasileira de obesidade, nutrição e emagrecimento Vol. 18; no. 114; p. 517
Main Authors A, Tossi, Gabriel Mayer, Griebler, Nathalia, Schestatsky, Pedro, Leal, Rodrigo, Munhoz, Samuel, Beraldo, Lucas, Adachi, Lauren Naomi, Pietta- Dias, Caroline
Format Journal Article
LanguageEnglish
Published Instituto Brasileiro de Pesquisa e Ensino em Fisiologia do Exercicio. IBPEFEX 01.05.2024
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Summary:Purpose: To investigate whether one session of transcranial direct current (tDCS) stimulation alone or combined with aerobic exercise (AE) could reduce food consumption and the perception of hunger and satiety in patients with binge eating disorder. Materials and Methods: Adult individuals with BED were recruited in a randomized, controlled, double-blind study. Participants received one session (1) active tDCS, (2) placebo and AE tDCS or (3) active tDCS and AE. tDCS was applied at 2mA / 20 min, with the anode over the right dorsolateral prefrontal cortex and the cathode over the contralateral supraorbital region. The AE was performed on a treadmill after tDCS, with initial warm-up and intensity of 60-65% of HRmax, repeating the evaluations at the end. Primary outcomes included measures of food intake and perceptions of hunger, satiety and desire. Results: The tDCS group had lower values of lean mass and triglycerides compared to the other groups. However, in relation to food intake, hunger, satiety throughout the day, and uncontrollable desire to eat, tDCS alone or combined were equally effective. Conclusions: tDCS alone or combined with AE improved clinical outcomes in patients with BED. To our knowledge, to date, this is the first study showing that the association of tDCS with aerobic exercise to relieve symptoms of patients with BE. Test record: ReBEC identifier RBR-3d8fd2. Key words: Transcranial direct current stimulation. tDCS. Exercise. Binge eating. Objetivo: Investigar se uma sessao de estimulacao transcraniana por corrente continua (ETCC) isolada ou combinada com exercicio aerobico (EA) poderia reduzir o consumo alimentar e a percepcao de fome e saciedade em pacientes com transtorno da compulsao alimentar periodica (TCAP). Materiais e Metodos: Individuos adultos com TCAP foram recrutados em um estudo randomizado, controlado e duplo-cego. Os participantes receberam uma sessao (1) tDCS ativo, (2) placebo e EA tDCS ou (3) tDCS ativo e EA. A ETCC foi aplicada a 2mA/20 min, com o anodo sobre o cortex pre-frontal dorsolateral direito e o catodo sobre a regiao supraorbitaria contralateral. O EA foi realizado em esteira apos ETCC, com aquecimento inicial e intensidade de 60-65% da FCmax, repetindo as avaliacoes ao final. Os resultados primarios incluiram medidas de ingestao de alimentos e percepcoes de fome, saciedade e desejo. Resultados: O grupo ETCC apresentou valores menores de massa magra e triglicerideos em relacao aos demais grupos. No entanto, em relacao a ingestao alimentar, fome, saciedade ao longo do dia e desejo incontrolavel de comer, a ETCC isolada ou combinada foram igualmente eficazes. Conclusoes: ETCC sozinho ou combinado com EA melhorou os resultados clinicos em pacientes com TCAP. Ao nosso conhecimento, ate o momento, este e o primeiro estudo mostrando que a associacao de tDCS com exercicios aerobicos para aliviar os sintomas de pacientes com EB. Registro de teste: identificador ReBEC RBR-3d8fd2. Palavras-chave: Estimulacao transcraniana por corrente continua. tDCS. Exercicio. Compulsao alimentar.
ISSN:1981-9919
1981-9919