Bioactivity of the Genus ITurnera/I: A Review of the Last 10 Years

• Published in: Pharmaceuticals (Basel, Switzerland) Vol. 16; no. 11
• Main Authors: Parra-Naranjo, Aída, Delgado-Montemayor, Cecilia, Salazar-Aranda, Ricardo, Waksman-Minsky, Noemí
• Format: Journal Article
• Language: English
• Published: MDPI AG 01.11.2023
• Subjects: Antioxidants; Biological products; Chemical properties; Evaluation; Fatty acids; Identification and classification; Isoflavones; Medicinal plants; Medicine, Botanic; Medicine, Herbal; Varieties; Mexico; Brazil; Iraq
• ISSN: 1424-8247; 1424-8247
• DOI: 10.3390/ph16111573

Turnera is a genus of plants whose biological activity has been widely studied. The importance of this genus, particularly Turnera diffusa, as a source of treatment for various conditions is evidenced by the large number of new studies that have evaluated its biological activity. Accordingly, the objective of this review was to compile the information published in the last ten years concerning the biological activities reported for Turnera spp. The present work includes 92 publications that evaluate 29 bioactivities and toxicological and genotoxic information on five species of this genus. Among the pharmacological effects reported, the antioxidant, hepatoprotective, neuroprotective, hypoglycemic, and aphrodisiac activities seem more promising. Phytochemicals and standardized plant extracts could offer alternative therapeutic remedies for various diseases. Although several flavonoids, cyanogenic glycosides, monoterpenoids, triterpenoids, and fatty acids have been isolated for Turnera plants, future research should focus on the identification of the main active principles responsible for these pharmacological activities, as well as to perform clinical trials to support the laboratory results.