The effect of injecting acute L-Carnitine on endurance time in rats exposed to different water temperature

Purpose: Carnitine plays an important role in lipid metabolism by transporting long-chain fatty acids into the mitochondria for beta-oxidation. The effect of carnitine on exercise capacity is not clear. The aim of this study was to explain effect of injecting acute L-Carnitine on endurance time in r...

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Published inOvidius University Annals, Series Physical Education and Sport/Science, Movement and Health Vol. 10; no. 1; p. S81
Main Authors Elif, Siktar, Erdinc, Siktar, Huseyin, Eroglu, Yunus, Oztasyonar
Format Journal Article
LanguageEnglish
Published Ovidius University of Constanta 01.01.2010
Subjects
Health aspects
Levocarnitine
Lipid metabolism
Physiological aspects
Turkey
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Summary:Purpose: Carnitine plays an important role in lipid metabolism by transporting long-chain fatty acids into the mitochondria for beta-oxidation. The effect of carnitine on exercise capacity is not clear. The aim of this study was to explain effect of injecting acute L-Carnitine on endurance time in rats exposed to different water temperature. Material and Methods: Six groups (E18[degrees]C, E28[degrees]C and E38[degrees]C groups made exhaustive swimming CE18[degrees]C, CE28[degrees]C and CE38[degrees]C groups given L-Carnitine and made exhaustive swimming exercises) were formed and a total of 36 Spraque Dawley male rats, weighing 250-300 g were used in this study. In the study, the L- Carnitine was given to the groups 1-1.5 hours before the exercises in the doses of 100 mg/kg by intraperitoneal (I.P.) way. Exhaustive swimming tests were made in a rectangle shaped glass water tank that was 80x60x60 [cm.sup.3]. The uncoordinated movements and staying under the water for 10 seconds without swimming at the surface were accepted as the exhaustion criteria of the rats. Results: In the rats of CE18[degrees]C group the endurance time increased significantly comparing with the E18[degrees]C (P <0.01). There was not significantly different among other groups Conclusion: This result suggests that carnitine may especially enhance the physical performance doing cold ambient. Carnitine might generate that effect by regulation lipid metabolism and mitocondrial functions. Keywords: L-Carnitine; endurance time; Exercise; Rat;water temperature.
ISSN:2285-777X