Metabolic Characterization of Anterior Mediastinal Masses by [.sup.18]F-FDG PET/CT/[.sup.18]F-FDG PET/BT ile Anterior Mediastinal Kitlelerin Metabolik Karakterizasyonu
Objectives: To evaluate the role of [.sup.18]F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for the diagnosis of anterior mediastinal masses. Methods: The oncological [.sup.18]F-FDG PET/CT images of 41 patients (17 women, 24 men; age: 16-83 years, mean age: 50.5...
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Published in | Molecular imaging and radionuclide therapy Vol. 29; no. 3; p. 105 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Galenos Yayinevi Tic. Ltd
01.10.2020
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Subjects | |
Online Access | Get full text |
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Summary: | Objectives: To evaluate the role of [.sup.18]F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for the diagnosis of anterior mediastinal masses. Methods: The oncological [.sup.18]F-FDG PET/CT images of 41 patients (17 women, 24 men; age: 16-83 years, mean age: 50.5[+ or -]19.5 years) who attended the nuclear medicine department between November 2016 and September 2017 were retrospectively evaluated for the metabolic characterization of their anterior mediastinal masses. Results: Based on our results, the lesions of 4 patients were benign [maximum standard uptake value ([SUV.sub.max]) <3] and that of 2 patients were non-tumoral (i.e., tuberculosis and sarcoidosis). The mean dimensions and the [SUV.sub.max] levels of the malignant lesions were 6.4[+ or -]3.7 cm and 11.9[+ or -]9.6, respectively. The pathological results for the malign tumors were thymus tumors (n=8), lymphoma (n=8), lung cancer (n=11), carcinoid metastasis (n=2), thyroid carcinoma (n=2), germ cell carcinoma (n=1), schwannoma (n=1), and sarcoma (n=1). The degree of [.sup.18]F-FDG accumulation could precisely identify the malign and benign tumors. Conclusion: Thus, contrary to the known causes, it is possible that anterior mediastinal masses originate from structures other than the anterior mediastinal structures. In this study, the lymphoma and lung carcinoma pathology were more frequent than thymic lesions. Keywords: Anterior mediastinum, mass, [.sup.18]F-FDG, PET/CT Amaç: Bu çalismada anterior mediastinal kitlelerin karakterizasyonunda [.sup.18]F-florodeoksiglukoz (FDG) pozitron emisyon tomografi/bilgisayarli tomografinin (PET/BT) rolü degerlendirilecektir. Yöntem: Anterior mediastinal kitle tanisiyla nükleer tip bölümüne Kasim 2016-Eylül 2017 tarihleri arasinda metabolik karakterizasyon amaciyla basvuran hastalarin onkolojik [.sup.18]F-FDG PET/BT görüntüleri geriye dönük olarak degerlendirildi. Kirk bir hasta (17 kadin, 24 erkek; 16-83, ortalama yas: 50,5[+ or -]19,5) çalismaya dahil edildi. Bulgular: Çalismaya dahil edilen hastalardan iki hastanin lezyonu benign olarak tanimlandi [maksimum standart alim degeri ([SUV.sub.maks]) <3] ve ikisinin patolojisi tümör disi lezyonlardi (tüberküloz ve sarkoidoz). Malignite tanisi konulan hastalarin kitlelerinin ortalama boyutu ve [SUV.sub.maks] k degerleri sirasiyla; 6,4[+ or -]3,7 cm ve 11,9[+ or -]9,6 idi. Malign tümörlerin patolojik tanilari; timik tumörler (n=8), lenfoma (n=8), akciger kanseri (n=11), karsinoid metastazi (n=2), tiroid karsinomu (n=2), germ hücreli tümör (n=1), schwannoma (n=1) ve sarkom (n=1) idi. Sonuç: Bilinen nedenlerin aksine anterior mediastinal kitlelerin patoloji sonuçlari anterior mediastinal yapilarin tümörlerinin veya karsinomlarinin disindaki patolojilerden kaynaklanabilir. Bu seride timik tümörlere göre lenfoma ve akciger karsinomu daha sik rastlanan patolojilerdi. Anahtar kelimeler: Anterior mediasten, kitle, [.ssup.18]F-FDG, PET/BT |
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ISSN: | 2146-1414 |
DOI: | 10.4274/mirt.galenos.2020.05657 |