Blood gas analysis, anion gap, and strong ion difference in horses treated with polyethylene glycol balanced solution ou solucoes eletroliticas enteral e parenteral

• Published in: Ciência rural Vol. 44; no. 6; p. 1086
• Main Authors: Gomes, Claudio Luis Nina, Filho, Jose Dantas Ribeiro, Faleiros, Rafael Resende, Dantas, Fernanda Timbo D'el Rey, Amorim, Lincoln da Silva, Dantas, Waleska de Melo Ferreira
• Format: Journal Article
• Language: Spanish
• Published: Universidade Federal de Santa Maria 01.06.2014
• Subjects: Blood gas analysis; Chlorides; Electrolytes; Polyethylene glycol
• ISSN: 0103-8478; 1678-4596

Large volumes of different electrolytes solutions are commonly used for ingesta hydration in horses with large colon impaction, but little is known about their consequences to blood acid-base balance. To evaluate the effects of PEG 3350 or enteral and parenteral electrolyte solutions on the blood gas analysis, anion gap and strong ion difference, five adult female horses were used in a 5x5 latin square design. The animals were divided in five groups and distributed to each of the following treatments: NaCl (0.9% sodium chloride solution); EES (enteral electrolyte solution), EES+LR (EES plus lactated Ringer's solution); PEG (balanced solution with PEG 3350) and PEG+LR (PEG plus lactated Ringer's solution). Treatments PEG or PEG + LR did not change or promoted minimal changes, while the EES caused a slight decrease in pH, but its association with lactated Ringer's solution induced increase in AG and SID values, as well as caused hypernatremia. In turn, the treatment NaCl generated metabolic acidosis. PEG 3350 did not alter the acid-base balance. Despite it's slight acidifying effect, the enteral electrolyte solution (EES) did not cause clinically relevant changes. Key words: Acid-base balance, cathartic, fluid therapy. Grandes volumes de diferentes solucoes eletroliticas sao comumente usados na hidratacao da ingesta em equinos com compactacao, mas pouco se sabe sobre suas consequencias sobre o equilibrio acido base sanguineo. Para avaliar os efeitos do PEG 3350 e solucoes eletroliticas enterais e parenterais sobre a hemogasometria, anion gap e diferenca de ions fortes, foram utilizadas cinco femeas adultas em um quadrado latino 5x5. Os animais foram distribuidos em cinco grupos e submetidos a cada um dos seguintes tratamentos: solucao NaCl (cloreto de sodio 0,9%); EES (solucao eletrolitica enteral); EES + RL (solucao eletrolitica enteral mais Ringer lactato); PEG 3350 (solucao balanceada com PEG 3350) e PEG + RL (PEG 3350 mais Ringer lactato). Os tratamentos PEG ou PEG + RL nao alteraram ou promoveram alteracoes minimas, enquanto a EES ocasionou discreta diminuicao no pH, mas sua associacao com Ringer lactato induziu o aumento nos valores do AG e DIF, alem de ocasionar hipernatremia. Por sua vez, o tratamento NaCl resultou em acidose metabolica hipercloremica. O PEG 3350 nao alterou o equilibrio acido base. Apesar do seu discreto efeito acidificante, a solucao eletrolitica enteral (EES) nao promoveu alteracao clinica relevante. Palavras-chave: Equilibrio acido base, catartico, hidratacao.