Phase Angle and Bioelectrical Impedance Vector Analysis Patients

Body composition and bioelectrical parameters are useful in nutritional assessment and monitoring of ALS patients. Phase angle (PhA) and bioelectrical impedance vector analysis (BIVA) have emerged as valuable tools for assessing nutritional status and prognosis in various patient populations, but th...

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Published inApplied sciences Vol. 14; no. 4
Main Authors Cunha, Thais Alves, Lopes, Márcia Marília Gomes Dantas, de Araújo Brito, Acsa Nara, Vermeulen-Serpa, Karina Marques, de Lima Vale, Sancha Helena, Brandão-Neto, José, Leite-Lais, Lucia
Format Journal Article
LanguageEnglish
Published MDPI AG 01.02.2024
Subjects
Amyotrophic lateral sclerosis
Analysis
Development and progression
Medical research
Medicine, Experimental
Nervous system diseases
Nutrition
Physiological aspects
Product/Service Evaluations
Prognosis
Brazil
Canada
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Summary:Body composition and bioelectrical parameters are useful in nutritional assessment and monitoring of ALS patients. Phase angle (PhA) and bioelectrical impedance vector analysis (BIVA) have emerged as valuable tools for assessing nutritional status and prognosis in various patient populations, but there is a lack of studies in rare neurodegenerative diseases. The purpose of this cross-sectional study was to investigate these bioelectrical parameters in patients with amyotrophic lateral sclerosis (ALS), compared with healthy peers. The tetrapolar impedance method was applied and bioimpedance analysis (BIA) was performed. Bioelectrical parameters were obtained (Resistance—R; Reactance—Xc) or calculated (PhA; BIVA). For BIVA, bivariate vectors and confidence ellipses were graphically represented. In addition, R and Xc were used to determine body composition (BC) (Fat Mass—FM; Fat-Free Mass—FFM; and Total Body Water—TBW). In this study, 40 participants were divided into two groups: case group (n = 20, ALS patients) and control group (n = 20, healthy subjects. Our main results showed that ALS patients presented low levels of BMI, FFM, R, and Xc adjusted by height (R/H, Xc/H), hydration, and cellularity, compared to the healthy subjects. Our findings highlight BC and bioelectrical parameters, including PhA and BIVA, as valuable indicators of nutrition status, which should be implemented in the nutrition care process of ALS patients during the disease course.
ISSN:2076-3417
2076-3417
DOI:10.3390/app14041545