The relationship between Geriatric Nutritional Risk Index

Background The role of the geriatric nutritional risk index (GNRI) as a prognostic factor in intensive care unit (ICU) patients with acute kidney injury (AKI) remains uncertain. Objectives The aim of this study was to investigate the impact of the GNRI on mortality outcomes in critically ill patient...

Full description

Saved in:
Bibliographic Details
Published inBMC anesthesiology Vol. 24; no. 1
Main Authors Zhao, Dong, Zhou, Dawei, Li, Tong, Wang, Chao, Fei, Shuyang
Format Journal Article
LanguageEnglish
Published BioMed Central Ltd 06.09.2024
Subjects
Hospital patients
Medical research
Medicine, Experimental
Mortality
Online databases
Patient outcomes
Prognosis
Online AccessGet full text

Cover

More Information
Summary:Background The role of the geriatric nutritional risk index (GNRI) as a prognostic factor in intensive care unit (ICU) patients with acute kidney injury (AKI) remains uncertain. Objectives The aim of this study was to investigate the impact of the GNRI on mortality outcomes in critically ill patients with AKI. Methods For this retrospective study, we included 12,058 patients who were diagnosed with AKI based on ICD-9 codes from the eICU Collaborative Research Database. Based on the values of GNRI, nutrition-related risks were categorized into four groups: major risk (GNRI < 82), moderate risk (82 [less than or equal to] GNRI < 92), low risk (92 [less than or equal to] GNRI < 98), and no risk (GNRI [greater than or equal to] 98). Multivariate analysis was used to evaluate the relationship between GNRI and outcomes. Results Patients with higher nutrition-related risk tended to be older, female, had lower blood pressure, lower body mass index, and more comorbidities. Multivariate analysis showed GNRI scores were associated with in-hospital mortality. (Major risk vs. No risk: OR, 95% CI: 1.90, 1.54-2.33, P < 0.001, P for trend < 0.001). Moreover, increased nutrition-related risk was negatively associated with the length of hospital stay (Coefficient: -0.033; P < 0.001) and the length of ICU stay (Coefficient: -0.108; P < 0.001). The association between GNRI scores and the risks of in-hospital mortality was consistent in all subgroups. Conclusions GNRI serves as a significant nutrition assessment tool that is pivotal to predicting the prognosis of critically ill patients with AKI. Keywords: Geriatric nutritional risk index (GNRI), Acute kidney injury (AKI), ICU, Mortality
ISSN:1471-2253
1471-2253
DOI:10.1186/s12871-024-02689-1