Light Absorption Analysis and Optimization of Ag@TiO[sub.2] Core-Shell Nanospheroid and Nanorod

• Published in: Nanomaterials (Basel, Switzerland) Vol. 14; no. 4
• Main Authors: Wumaier, Dilishati, Tuersun, Paerhatijiang, Li, Shuyuan, Li, Yixuan, Wang, Meng, Xu, Dibo
• Format: Journal Article
• Language: English
• Published: MDPI AG 01.02.2024
• Subjects: Absorption; Analysis; Cancer; Care and treatment; Finite element method; Mechanical properties; Nanoparticles; Nanorods; Optical properties; Silver; Titanium dioxide; China
• ISSN: 2079-4991; 2079-4991
• DOI: 10.3390/nano14040325

For photothermal therapy of cancer, it is necessary to find Ag @TiO[sub.2] core-shell nanoparticles that can freely tune the resonance wavelength within the near-infrared biological window. In this paper, the finite element method and the size-dependent refractive index of metal nanoparticles were used to theoretically investigate the effects of the core material, core length, core aspect ratio, shell thickness, refractive index of the surrounding medium, and the particle orientation on the light absorption properties of Ag@TiO[sub.2] core-shell nanospheroid and nanorod. The calculations show that the position and intensity of the light absorption resonance peaks can be freely tuned within the first and second biological windows by changing the above-mentioned parameters. Two laser wavelengths commonly used in photothermal therapy, 808 nm (first biological window) and 1064 nm (second biological window), were selected to optimize the core length and aspect ratio of Ag@TiO[sub.2] core-shell nanospheroid and nanorod. It was found that the optimized Ag@TiO[sub.2] core-shell nanospheroid has a stronger light absorption capacity at the laser wavelengths of 808 nm and 1064 nm. The optimized Ag@TiO[sub.2] core-shell nanoparticles can be used as ideal therapeutic agents in photothermal therapy.