Prevalence of Vitamin D Deficiency and Seasonality Effect in First Trimester Pregnant Women Referring to a Tertiary Health Care Institution/Ucuncu Basamak Saglik Kurulusuna Basvuran Ilk Trimesterdeki Gebe Kadinlarin D Vitamini Eksikligi Prevalansi ve Mevsimsellik Etkisi

• Published in: Southern Clinics of Istanbul Eurasia (SCIE) Vol. 35; no. 2; p. 186
• Main Authors: Turan, Kasim, Kuru, Betul
• Format: Journal Article
• Language: Turkish
• Published: KARE Publishing 01.06.2024
• Subjects: Environmental aspects; Obstetrical research; Physiological aspects; Pregnancy; Statistics; Vitamin D deficiency; Turkey
• ISSN: 2587-0998
• DOI: 10.14744/scie.2024.90217

Objective: We aim to investigate the prevalence of low vitamin D levels in pregnant women receiving medical care at a tertiary hospital by analyzing the seasonal variations in these levels. Methods: This study was conducted at the Obstetrics and Gynecology outpatient facility of a tertiary medical institution between February 2020 and February 2024. The demographic data, including maternal age, parity, gestational age, smoking status, vitamin D level, and seasonal information, were duly captured from the first antenatal medical examination records. Results: After the exclusion of individuals who did not meet the predetermined criteria, a total of 1101 pregnant women were selected to partake in the study. Among the pregnant women, a large proportion (866, 79%) had serum 25(OH)D concentrations lower than 20 ng/mL, with an additional 132 out of 866 (15.2%) having levels below 5 ng/mL. The overall sample group showed a mean vitamin level of 13.71[+ or -]9.18, while the subset of participants with a vitamin D deficiency had a recorded value of 9.85[+ or -]4.62. During the fall and summer seasons, a considerable 82% and 72.8% respectively exhibited a significant prevalence of hypovitaminosis D. The trend curve for the seasonal vitamin D levels of the vitamin D-deficient group shows a relatively flat pattern, with an [R.sup.2]=0.0097 score. Conclusion: The findings from our investigation corroborate the implementation of prenatal multivitamins enriched with vitamin D as a preventive measure against musculoskeletal and non-musculoskeletal conditions for maternal and neonatal health. Keywords: Hypovitaminosis D; pregnancy; prevalence; seasonal; vitamin D. Amac: Ucuncu basamak bir hastanede tibbi bakim alan gebe kadinlarda dusuk D vitamini duzeylerinin prevalansini ve bu seviyelerdeki mevsimsel degisimleri analiz ederek degerlendirmeyi amacladik. Gerec ve Yontem: Bu calisma, Subat 2020 ile Subat 2024 tarihleri arasinda ucuncu basamak bir tip kurulusunun Kadin Hastaliklari ve Dogum polikliniginde yurutuldu. Ilk antenatal kontrol sirasinda yas, parite, gestasyonel hafta, sigara kullanimi bilgisi, D vitamini seviyesi ve mevsim bilgisi kayit altina alindi. Bulgular: Calismamiza 1101 gebe dahil edildi. Bu gebe kadinlarin 866'inda (%79) D vitamini eksikligi tespit edilirken, 866 gebenin 132'sinde D vitamini seviyesi 5 ng/ml'nin altinda tespit edildi. Toplam calisma grubunda vitamin D degeri ortalamasi 13.71+/-9.18 iken, vitamin D eksikligi olan grupta 9.85+/-4.62 idi. Yaz ve sonbahar aylarindaki hipovitaminozis D prevalansi ise sirasiyla %72.8 ve %82 olarak tespit edildi. D vitamini eksikligi olan grubun mevsimsel D vitamini seviyelerinin ortalamasinin egilim egrisi R2=0.0097 degeriyle rolatif olarak sabit kalmaktadir. Sonuc: Arastirmamizdan elde edilen bulgular, anne ve yenidogan kas-iskelet sistemi ve kas-iskelet sistemi disi sagligi icin D vitamini ile zenginlestirilmis dogum oncesi multivitaminlerin uygulanmasini desteklemektedir. Anahtar Sozcukler: D vitamini; gebelik; hipovitaminozis D; mevsimsellik; prevalans.