Hypothalamic Regulation of Obesity

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• Subjects: 5xFAD; adiponectin; adiposity; AGF; Alzheimer’s disease; astrocyte; astrocytes; Biology, life sciences; body weight; diabetes; energy balance; energy expenditure; energy homeostasis; energy metabolism; estradiol; fasting; food intake; food intake and obesity; gliosis; glucose homeostasis; glycolysis; gut–brain axis; high-fat diet; hypothalamus; insulin sensitivity; insulin signaling; leptin; Mathematics and Science; metabolic diseases; metabolism; microbiota; microglia; microglia–neuron communication; n/a; neuroinflammation; neurons; neuropeptide; neurosecretory protein GL; nociceptin/orphanin FQ; nutrient sensing; obesity; pituitary adenylate cyclase-activating polypeptide; POMC neuron; Reference, Information and Interdisciplinary subjects; Research and information: general; sex difference; SF1 neurons; SIRT1; SIRT6; transcriptomic; type 2 diabetes; ventromedial hypothalamus nucleus
• ISBN: 9783036573939; 3036573925; 9783036573922; 3036573933
• DOI: 10.3390/books978-3-0365-7392-2

The manuscripts published in this reprint provide new insights into the hypothalamic neuronal and non-neuronal pathways involved in the pathophysiology and development of obesity and related diseases such as diabetes. Via four original papers, six review manuscripts, and one perspective, this reprint will substantially contribute to the identification of novel therapeutic targets in the hypothalamus and novel approaches to combatting the progression of human obesity.