Secondary syphilis presenting as nephrotic syndrome

Nephrotic syndrome is characterized by an increase in glomerular capillary permeability to proteins, especially albumin, which ultimately leads to sufficient proteinuria to exceed hepatic synthetic replacement capacity. The resultant hypoalbuminemia and corresponding hypo-oncotic pressure load to ge...

Full description

Saved in:
Bibliographic Details
Published inThe Western journal of medicine Vol. 156; no. 6; pp. 654 - 655
Main Authors Magarian, G. J., Marr, C.
Format Journal Article
LanguageEnglish
Published United States BMJ Publishing Group Ltd 01.06.1992
BMJ Publishing Group LTD
Subjects
Complications and side effects
Humans
Male
Middle Aged
Nephrotic syndrome
Nephrotic Syndrome - etiology
Physiological aspects
Syphilis
Syphilis - complications
Syphilis - diagnosis
Treponema pallidum
Online AccessGet full text

Cover

More Information
Summary:Nephrotic syndrome is characterized by an increase in glomerular capillary permeability to proteins, especially albumin, which ultimately leads to sufficient proteinuria to exceed hepatic synthetic replacement capacity. The resultant hypoalbuminemia and corresponding hypo-oncotic pressure load to generalized edema formation. Because of the rarity of nephrotic syndrome from secondary or latent syphilis and the uncertainty of its clinical course with antisyphilitic therapy, we report a case of the acute onset of nephrotic syndrome in a middle-aged man whose clinical course and serologic status were observed closely for a year after treatment with penicillin.
Bibliography:PMID:1615665
istex:697D600D2E832B8DD4160C2742C164018D02E154
ark:/67375/NVC-T0MV1ND7-3
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Case Study-2
ObjectType-Feature-4
ObjectType-Report-1
ObjectType-Article-3
ISSN:0093-0415
1476-2978