Laryngeal paraganglioma: report of an unusual entity

Paragangliomas are rare in the larynx. When they do occur there, the most common subsite is the supraglottic compartment. Unlike other neuroendocrine tumors of the larynx, laryngeal paragangliomas are three times as common in women as in men. Although a preoperative biopsy is often performed to esta...

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Bibliographic Details
Published inEar, nose, & throat journal Vol. 89; no. 11; pp. 550 - 552
Main Authors Kaytaz, Asim, Karaman, Emin, Edizer, Deniz Tuna, Haciyev, Yusuf, Oz, Buge
Format Journal Article
LanguageEnglish
Published United States Sage Publications, Inc 01.11.2010
SAGE PUBLICATIONS, INC
Subjects
Care and treatment
Chromaffin cells
Diagnosis
Female
Health aspects
Humans
Laryngeal cancer
Laryngeal Neoplasms - diagnosis
Laryngeal Neoplasms - surgery
Larynx
Male
Medical imaging
Paraganglioma - diagnosis
Paraganglioma - surgery
Radiation therapy
Risk factors
Tumors
Veins & arteries
Turkey
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Summary:Paragangliomas are rare in the larynx. When they do occur there, the most common subsite is the supraglottic compartment. Unlike other neuroendocrine tumors of the larynx, laryngeal paragangliomas are three times as common in women as in men. Although a preoperative biopsy is often performed to establish the diagnosis, this procedure carries a considerable risk of bleeding, which may necessitate a tracheotomy to secure the airway. Immunohistochemical staining is useful in the differential diagnosis to distinguish a paraganglioma from other neuroendocrine tumors. Computed tomography and/or magnetic resonance imaging with preoperative angiography and possible embolization are important to obtain prior to treatment. Surgical excision is the treatment of choice.
Bibliography:ObjectType-Article-1
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ISSN:0145-5613
1942-7522