Microbial Cell Factories for Diol Production

Diols are compounds with two hydroxyl groups and have a wide range of appealing applications as chemicals and fuels. In particular, five low molecular diol compounds, namely 1,3-propanediol (1,3-PDO), 1,2-propanediol (1,2-PDO), 2,3-butanediol (2,3-BDO), 1,3-butanediol (1,3-BDO), and 1,4-butanediol (...

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Bibliographic Details
Published inAdvances in biochemical engineering, biotechnology Vol. 155; p. 165
Main Authors Sabra, W, Groeger, C, Zeng, An-Ping
Format Journal Article
LanguageEnglish
Published Germany 01.01.2016
Subjects
Bacteria - genetics
Bacteria - metabolism
Butylene Glycols - metabolism
Metabolic Engineering - methods
Propylene Glycols - metabolism
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Summary:Diols are compounds with two hydroxyl groups and have a wide range of appealing applications as chemicals and fuels. In particular, five low molecular diol compounds, namely 1,3-propanediol (1,3-PDO), 1,2-propanediol (1,2-PDO), 2,3-butanediol (2,3-BDO), 1,3-butanediol (1,3-BDO), and 1,4-butanediol (1,4-BDO), can be biotechnologically produced by direct microbial bioconversion of renewable materials. In this review, we summarize recent developments in the microbial production of diols, especially regarding the engineering of typical microbial strains as cell factory and the development of corresponding bioconversion processes.
ISSN:0724-6145
DOI:10.1007/10_2015_330