Osteoarthritis: a review of treatment options

Osteoarthritis (OA) is the most common form of arthritis and the leading cause of disability in the United States, especially among older adults. Treatment options have primarily focused on alleviating the pain often associated with this condition. Acetaminophen and nonsteroidal antiinflammatory dru...

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Bibliographic Details
Published inFormulary (Cleveland, Ohio) Vol. 44; no. 5; p. 143
Main Authors Seed, Sheila M, Dunican, Kaelen C, Lynch, Ann M
Format Journal Article
LanguageEnglish
Published North Olmsted Intellisphere, LLC 01.05.2009
MultiMedia Healthcare Inc
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Summary:Osteoarthritis (OA) is the most common form of arthritis and the leading cause of disability in the United States, especially among older adults. Treatment options have primarily focused on alleviating the pain often associated with this condition. Acetaminophen and nonsteroidal antiinflammatory drugs (NSAIDs) are often employed for relief of mild-to-moderate pain associated with OA. NSAIDs are typically more effective than acetaminophen; however, because of adverse effects associated with long-term use of NSAIDs, acetaminophen is considered first-line therapy. Safety concerns over traditional pharmacotherapeutic agents used in the management of OA, such as NSAIDs and opioids have led healthcare professionals to seek other options. Trials of disease-modulating agents that focus on preventing further damage to the joints have the potential to change how this disease state is managed. This article reviews nonpharmacologic and pharmacologic approaches to management of OA of the knee and hip. [PUBLICATION ABSTRACT]
ISSN:1082-801X
1938-1166