Neutrophil to lymphocyte ratio in Behçet's disease as a marker of disease activity

Behçet's disease (BD) is a rare autoimmune disease. The neutrophil to lymphocyte ratio (NLR) is used as a marker of inflammation in several diseases nowadays. This study investigated the NLR as an inflammation marker in BD. Sixty-five patients diagnosed with BD and 100 healthy subjects were enr...

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Published inActa dermatovenerologica Alpina, Panonica, et Adriatica Vol. 23; no. 4; pp. 65 - 67
Main Authors Rifaioglu, Emine Nur, Bülbül Şen, Bilge, Ekiz, Özlem, Cigdem Dogramaci, Asena
Format Journal Article
LanguageEnglish
Published Slovenia Association of Slovenian Dermatovenerologists 01.01.2014
Subjects
Adult
Behcet Syndrome - immunology
Behcet's syndrome
Biological markers
Development and progression
Female
Humans
Leukocyte Count
Lymphocyte Count
Lymphocytes
Male
Measurement
Medical research
Middle Aged
Neutrophils
Retrospective Studies
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Summary:Behçet's disease (BD) is a rare autoimmune disease. The neutrophil to lymphocyte ratio (NLR) is used as a marker of inflammation in several diseases nowadays. This study investigated the NLR as an inflammation marker in BD. Sixty-five patients diagnosed with BD and 100 healthy subjects were enrolled in this study retrospectively. The white blood cell (WBC), neutrophil, and lymphocyte counts were recorded, and the NLR was calculated from these parameters. The NLR and the CRP and WBC levels were higher in patients with BD than controls (p < 0.001, p < 0.001, and p = 0.026, respectively). In addition, the NLR was higher in patients with active BD than in those with inactive BD (p = 0.033). The results demonstrate that the NLR is higher in patients with active BD compared to controls and those with inactive BD.
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ISSN:1318-4458
1581-2979
DOI:10.15570/actaapa.2014.16