Comparison of microalbuminuria with hs-CRP and low density lipoprotein levels in nondiabetic, nonhypertensive myocardial infarction patients

• Published in: Journal of cardiovascular disease research Vol. 3; no. 4; pp. 287 - 289
• Main Authors: Goud, B K Manjunatha, Nayal, Bhavna, Devi, Oinam S, Devaki, R N, Avinash, S S, Satisha, T G, Raghuveer, C V
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.10.2012; Elsevier Limited; Medknow Publications & Media Pvt Ltd
• Subjects: Albuminuria; Biological markers; C-reactive protein; Cardiovascular disease; Cholesterol; Cholesterol, LDL; Diagnosis; Health aspects; Heart attack; Heart attacks; Lipids; Low density lipoprotein; Original; Risk factors; India; Non diabetics; Low density lipoprotein cholesterol; microalbumin; myocardial infarction
• ISSN: 0975-3583; 0976-2833
• DOI: 10.4103/0975-3583.102702

Microalbuminuria (MA), defined as urine albumin to urine creatinine ratio (UACR) of 30 to 300 mg/G of creatinine, is an established risk factor for cardiovascular morbidity and mortality and for end-stage renal disease in individuals with an adverse cardiovascular risk profile such as those with hypertension or/and diabetes mellitus. Thirty five patients were included in the study and equal number of age- and sex-matched controls were also included. 2 ml of venous blood was collected for hs-CRP determination and early morning mid stream urine sample was collected under strict aseptic precautions. The lipid profile was estimated in cobas autoanalyzer. There was significant increase in levels of Low density lipoprotein (LDL) cholesterol, microalbumin, and hs-CRP (P< 0.001) in patients with myocardial infarction compared to healthy controls. Therefore, MA and hsCRP evaluation may have potential role in improving cardiovascular risk prediction, when used along with traditional lipid profiles.