Antibacterial activity of propolis extracts from the south of Portugal

To examine the antibacterial activity of diverse extracts of propolis harvested at winter and spring from several locations of Algarve, Portugal, against Gram-negative and Gram-positive bacteria was the main goal of the present work. For such, the antibacterial activity was determined by agar diffus...

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Published inPakistan journal of pharmaceutical sciences Vol. 30; no. 1; pp. 1 - 9
Main Authors Oliveira, Ana Vanessa, Ferreira, Ana Luisa, Nunes, Susana, Dandlen, Susana Anahi, Miguel, da Graca da Graca, Faleiro, Maria Leonor
Format Journal Article
LanguageEnglish
Published Pakistan Pakistan Journal of Pharmaceutical Sciences 01.01.2017
Subjects
Anti-Bacterial Agents - isolation & purification
Anti-Bacterial Agents - pharmacology
Disk Diffusion Antimicrobial Tests
Dose-Response Relationship, Drug
Ethanol - chemistry
Gram-Negative Bacteria - drug effects
Gram-Negative Bacteria - growth & development
Gram-Positive Bacteria - drug effects
Gram-Positive Bacteria - growth & development
Helicobacter pylori - drug effects
Helicobacter pylori - growth & development
Methanol - chemistry
Physiological aspects
Portugal
Properties
Propolis
Propolis - chemistry
Solvents - chemistry
Portugal
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Summary:To examine the antibacterial activity of diverse extracts of propolis harvested at winter and spring from several locations of Algarve, Portugal, against Gram-negative and Gram-positive bacteria was the main goal of the present work. For such, the antibacterial activity was determined by agar diffusion. The results showed that all tested bacterial strains showed susceptibility to diluted propolis extracts and in a dose-dependent manner. Two propolis samples collected at springtime showed higher antibacterial activity, in comparison with samples harvested at wintertime. Ethanolic and methanolic extracts have a very similar activity (P<0.05). Helicobacter pylori strains J99 and 26695 were the most susceptible strains to the tested extracts (33.67±2.52 mm and 35.67±0.58mm, respectively). This study constitutes the first approach of the biological activities of Portuguese propolis from the Algarve region and evidences its potential use to combat bacterial infections, in particular against the gastric pathogen H. pylori.
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ISSN:1011-601X