Crystal-Induced Arthritides in the Elderly: An Update

The prevalence of gout increases with age. After the serum concentration of urate exceeds the saturation or solubility point, it deposits in and around the joints. Presentation in the elderly is often atypical and challenging to diagnose. Treatment depends on disease stage, health status, and comorb...

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Bibliographic Details
Published inRheumatic diseases clinics of North America Vol. 44; no. 3; p. 489
Main Authors El-Zawawy, Hossam, Mandell, Brian F
Format Journal Article
LanguageEnglish
Published United States 01.08.2018
Subjects
Comorbidities
Treat to target
Gout
Geriatrics
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Summary:The prevalence of gout increases with age. After the serum concentration of urate exceeds the saturation or solubility point, it deposits in and around the joints. Presentation in the elderly is often atypical and challenging to diagnose. Treatment depends on disease stage, health status, and comorbidities. Elderly patients often have several confounding issues; treatment decisions can be complicated and therapeutic options limited. To prevent recurrence, serum concentration of urate should be maintained well below the saturation threshold of 6.8 mg/dL, leading to dissolution of urate deposits and preventing recurrence.
ISSN:1558-3163
DOI:10.1016/j.rdc.2018.03.007