A double-blind comparison of clebopride and placebo in dyspepsia secondary to delayed gastric emptying

Seventy-six patients suffering from dyspeptic symptoms secondary to roentgenologically demonstrated delayed gastric emptying were treated with clebopride (0.5 mg TID) or with placebo during a three-month double-blind trial. Clebopride was more effective (P less than or equal to 0.001) than placebo i...

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Bibliographic Details
Published inClinical therapeutics Vol. 7; no. 4; p. 468
Main Authors Bavestrello, L, Caimi, L, Barbera, A
Format Journal Article
LanguageEnglish
Published United States 1985
Subjects
Adolescent
Adult
Aged
Antiemetics - adverse effects
Antiemetics - therapeutic use
Benzamides - adverse effects
Benzamides - therapeutic use
Clinical Trials as Topic
Double-Blind Method
Dyspepsia - drug therapy
Dyspepsia - etiology
Female
Gastric Emptying - drug effects
Humans
Male
Middle Aged
Random Allocation
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Summary:Seventy-six patients suffering from dyspeptic symptoms secondary to roentgenologically demonstrated delayed gastric emptying were treated with clebopride (0.5 mg TID) or with placebo during a three-month double-blind trial. Clebopride was more effective (P less than or equal to 0.001) than placebo in reducing or relieving symptoms and roentgenological findings associated with delayed gastric emptying. No interactions of clebopride with concomitant drugs or coexisting disorders were observed, and the incidence of side effects was low. We conclude that clebopride will be beneficial in the management of patients with delayed gastric emptying.
ISSN:0149-2918